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Introduction

From the ages of 18 to 30 (2013 to 2025) I tried out pretty much every available product, treatment and natural guide for Premature Ejaculation (PE) there exists. Here’s the summary, so you don’t have to learn through your own trial and error.
What causes PE?
The exact cause is unknown, but it’s a mixture of low serotonin levels in your mind/body (as evidenced by the prolonging effects of SSRIs like dapoxetine, MDMA, Kanna etc), higher levels of anxiety, higher sensitivity, and a lack of control over your sympathetic nervous system (which causesfaster breathing, heart rate etc - triggering the fight or flight response, and also your ejaculation response).
 

Summary / Best Stack

Premature ejaculation is usually defined as sub <2 min. Firstly there are natural techniques you can try - including breathing techniques, going mutilpe rounds and kegels. There are also various natural guides you can try, listed below. For me personally the natural techniques are add-ons

There are various products you can use also, split primarily into two camps - serotonin effectors and desensitising sprays:

- Dapoxetine (a strong serotonin effector, will likely fix your issues, but side effects like head aches). Need to take 2hrs before.

- Kanna - another serotonin effector like Dapoxetine, but not as strong. Works in 30 mins.

- Desensitising sprays. Loads out there - lidocaine, cloves, gambir.
 
If you gain better control of your seratonin system, you gain control of your ejaculation reflex.

Best stack:

For me dapoxetine works on its own, and can be used when you have 2+ hours advanced warning.
For shorter times and fewer side effects, Kanna paired with a desensitising spray works well. For desensiting sprays, I prefer lidocaine sprays due to the short time it takes to take effect (10 mins), but a lot of the others work well too. Clove based sprays like PYT take longer to take effect (30 mins), but can give the same effect but as lidocaine but slightly more feeling. With Kanna + a desensitising spray I get pretty much the same level of control as dapoxetine.
Combined with these you can try out some of the natural techniques listed below.
 

Seratonin Products

Dapoxetine
 
Kanna
 
How long it takes to kick in and Duration
 

Desenzitising Sprays

lidocaine

 
 

cloves

 
gambir
 

others / other herbal

 

Natural remedies - Kegels, breathing, therapy etc

breathing
kegels
mutliple rounds, distracting yuor mind

Natural protocols/guides

 
 
 

PE causes and science